BEGIN:VCALENDAR VERSION:2.0 PRODID:-//hacksw/handcal//NONSGML v1.0//EN CALSCALE:GREGORIAN BEGIN:VEVENT LOCATION:Online / Moscow\, st. Ordzhonikidze 3\, Hall 2 (room 708) DESCRIPTION:In this lecture\, we describe novel all-on-resin strategies permitting the synthesis of super potent (nano- and picomolar) tubulysin and dolastatin analogs and their functionalization with cleavable linkers that allow their traceless release after the selective internalization into cancer cells. We also present synthetic methods towards novel targeting peptides and their conjugates to the cytotoxic payloads. DTSTART:20231002T140000Z DTEND:20231002T153000Z SUMMARY:Lecture “Multicomponent Reactions in the Development of Peptide Pharmaceuticals” URL;VALUE=URI:/media/events/lecture-multicomponent-reactions-in-the-development-of-peptide-pharmaceuticals/ DTSTAMP:20260825T002919Z UID:6a8cb7af82075 END:VEVENT END:VCALENDAR