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Electromechanical Model of Cardiac Muscle Tissue with Mechano-Electrical Feedback

Electromechanical Model of Cardiac Muscle Tissue with Mechano-Electrical Feedback

On 12th of March 2020 one of the leading experts of RUDN Research Center Mathematical Modelling in Biomedicine Fyodor A. Syomin held an open lecture Electromechanical Model of Cardiac Muscle Tissue with Mechano-Electrical Feedback

Many heart diseases are associated with arrhythmias of various nature. For a deeper understanding of the causes of arrhythmias formation and conditions of their persistence, as well as for the development of accurate personalized models that could be applied in medical practice, a detailed model of myocardial electromechanics is needed. Such a model should consider the interconnections of processes of various nature, and, if possible, be quite simple from a computational point of view. RUDN mathematicians present a prototype of the electromechanical model of the myocardium, in which the description of the electrical activation of the cardiac muscle by a simple Aliev-Panfilov model is coupled with a new model of myocardial mechanics developed by the group of the report author. The simulation results for the appearance and propagation of spiral waves of the action potential in deformable myocardium are shown. The effects of mechano-electrical feedback taken into account and introduced at the levels of the cell and tissue are demonstrated.

Main Publications View all
15 Nov 2017
RUDN University scientists publish results of their scientific researches in highly-recognized in whole world and indexed in international databases journals (Web of Science, Scopus ect.). That, of course, corresponds to the high status of the University and its international recognition. Publications of June-September 2017 ( In Journals of categories Q1-Q3)
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Research and Innovative Activity View all
30 Dec 2020
In 2017, RUDN University scientists constructed a new explicit second-order precision difference scheme using modern computer algebra methods for 2-dimensional Navier-Stokes equations (NSE) [1]. This year, our mathematicians used a new scheme [2] to construct a numerical solution to the Cauchy problem with initial data (for t=0) as satisfying the continuity equation. Scientists managed to achieve previously unattainable accuracy of the continuity equation.
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08 Aug
From nexium to generics: a young RUDN scientist has proposed a way to reduce the cost of pediatric reflux treatment

XXXII Russian National Congress “Man and Medicine” was held in Moscow, a key event for the medical and pharmaceutical community. Pavel Murzov, an assistant professor at the Department of Pharmacy Management and Economics at RUDN University, became the winner among thousands of participants. He presented a study on the rational use of Proton Pump Inhibitors (PPIs) in pediatrics.

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08 Aug
SDGs - a strategic landmark for RUDN University scientists

Senezh Management Workshop completed the fourth module of the Management Talent Pool Development Program in Science, Technology, and Higher Education. The only participant from RUDN University was Alexander L. Chupin, PhD in Economics, Deputy Dean for Research at the Faculty of Economics.

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20 Apr
A modern university in the context of the transformation of the global scientific and educational landscape: how to ensure sustainable development?

On February 6-7, RUDN University hosted an international scientific and practical conference “Modern university mission in the context of transformation challenges in a multipolar world”. The event was timed to coincide with the 65th anniversary of the founding of RUDN University.

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